Anti-CCAR1 Antibody

Rs. 45,619.00
SKU stj115556

General Information

Product name Anti-CCAR1 Antibody
Short Description Rabbit polyclonal to CCAR1
Description
Applications WB,IF,IP
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:50 - 1:100
Protein Name Cell division cycle and apoptosis regulator protein 1Cell cycle and apoptosis regulatory protein 1CARP-1Death inducer with SAP domain
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CCAR1 (NP_060707.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 132.8 kDa
Database Links
Alternative Names CCAR1Cell division cycle and apoptosis regulator protein 1 antibodyCell cycle and apoptosis regulatory protein 1 antibodyCARP-1 antibodyDeath inducer with SAP domainCCAR1 antibodyCARP1 antibodyDIS
Function Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter, Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone, Also functions as a p53 coactivator, May thus play an important role in transcriptional regulation (By similarity), May be involved in apoptosis signaling in the presence of the reinoid CD437, Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A, Plays a role in cell cycle progression and/or cell proliferation.
Cellular Localization Cytoplasm, perinuclear region
Tissue Specificity Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia, expression is regulated by growth factors.
Swiss-Prot Key

 

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