Anti-CCAR1 Antibody

Rs. 68,577.00
SKU stj72101

General Information

Product name Anti-CCAR1 Antibody
Short Description Goat polyclonal to CCAR1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-CCAR1 Antibody
Immunogen internal region (near C-Terminus)
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 132.8 kDa
Database Links
Alternative Names CCAR1Cell division cycle and apoptosis regulator protein 1 antibodyCell cycle and apoptosis regulatory protein 1 antibodyCARP-1 antibodyDeath inducer with SAP domainCCAR1 antibodyCARP1 antibodyDIS
Function Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter, Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone, Also functions as a p53 coactivator, May thus play an important role in transcriptional regulation (By similarity), May be involved in apoptosis signaling in the presence of the reinoid CD437, Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A, Plays a role in cell cycle progression and/or cell proliferation ,
Cellular Localization Cytoplasm, perinuclear region
Tissue Specificity Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia, expression is regulated by growth factors,
Swiss-Prot Key

 

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