Anti-CCKBR Antibody

Rs. 68,577.00
SKU stj70710

General Information

Product name Anti-CCKBR Antibody
Short Description Goat polyclonal to CCKBR
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-CCKBR Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 48.4 kDa
Database Links
Alternative Names CCKBRGastrin/cholecystokinin type B receptor antibodyCCK-B receptor antibodyCCK-BR antibodyCholecystokinin-2 receptor antibodyCCK2-RCCKBR antibodyCCKRB
Function Receptor for gastrin and cholecystokinin, The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity, This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Cellular Localization Cell membrane
Tissue Specificity Isoform 1 is expressed in brain, pancreas, stomach, the colon cancer cell line lovo and the t-lymphoblastoma jurkat, but not in heart, placenta, liver, lung, skeletal muscle, kidney or the stomach cancer cell line ags, expressed at high levels in the small cell lung cancer cell line nci-h510, at lower levels in nci-h345, nci-h69 and glc-28 cell lines, not expressed in glc-19 cell line, within the stomach, expressed at high levels in the mucosa of the gastric fundus and at low levels in the antrum and duodenum, isoform 2 is present in pancreatic cancer cells and colorectal cancer cells, but not in normal pancreas or colonic mucosa, isoform 3 is expressed in brain, pancreas, stomach, the stomach cancer cell line ags and the colon cancer cell line lovo,
Swiss-Prot Key

 

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