Anti-CCL3L1 Antibody

Rs. 45,619.00
SKU stj22935

General Information

Product name Anti-CCL3L1 Antibody
Short Description Rabbit polyclonal to CCL3L1
Description This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants.
Applications WB
Dilution range WB 1:200 - 1:500
Protein Name Anti-CCL3L1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 24-93 of human CCL3L1 (NP_066286.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 10.2 kDa
Database Links
Alternative Names CCL3L1C-C motif chemokine 3-like 1 antibodyG0/G1 switch regulatory protein 19-2 antibodyLD78-beta(1-70 antibody antibodyPAT 464.2 antibodySmall-inducible cytokine A3-like 1 antibodyTonsillar lymphocyte LD78 beta proteinCCL3L1 antibodyD17S1718 antibodyG0S19-2 antibodySCYA3L1; antibodyCCL3L3
Function Chemotactic for lymphocytes and monocytes, Is a ligand for CCR1, CCR3 and CCR5, Is an inhibitor of HIV-1-infection, The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection, LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
Cellular Localization Secreted
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed