General Information
| Product name | Anti-CCL4 Antibody |
|---|---|
| Short Description | Rabbit polyclonal to CCL4 |
| Description | The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. |
| Applications | WB,IHC |
| Dilution range | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Protein Name | Anti-CCL4 Antibody |
| Immunogen | A synthetic peptide of human CCL4 |
| Storage Instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Type of Usage | For Research Use Only (RUO). |
Product Properties
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Isotype | IgG |
| Formulation | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Target
| Gene ID | |
|---|---|
| Gene Symbol | |
| Molecular Weight | 10.2 kDa |
| Database Links | |
| Alternative Names | CCL4C-C motif chemokine 4 antibodyG-26 T-lymphocyte-secreted protein antibodyHC21 antibodyLymphocyte activation gene 1 protein antibodyLAG-1 antibodyMIP-1-beta(1-69 antibody antibodyMacrophage inflammatory protein 1-beta antibodyMIP-1-beta antibodyPAT 744 antibodyProtein H400 antibodySIS-gamma antibodySmall-inducible cytokine A4 antibodyT-cell activation protein 2 antibodyACT-2CCL4 antibodyLAG1 antibodyMIP1B antibodySCYA4 |
| Function | Monokine with inflammatory and chemokinetic properties, Binds to CCR5, One of the major HIV-suppressive factors produced by CD8+ T-cells, Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV), The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells, MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
| Cellular Localization | Secreted |
| Tissue Specificity | |
| Swiss-Prot Key |