Anti-CCL8 Antibody

Rs. 45,619.00
SKU stj29057

General Information

Product name Anti-CCL8 Antibody
Short Description Rabbit polyclonal to CCL8
Description This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:100
Protein Name Anti-CCL8 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 23-99 of human CCL8 (NP_005614.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 11.2 kDa
Database Links
Alternative Names CCL8C-C motif chemokine 8 antibodyHC14 antibodyMonocyte chemoattractant protein 2 antibodyMonocyte chemotactic protein 2 antibodyMCP-2 antibodySmall-inducible cytokine A8CCL8 antibodyMCP2 antibodySCYA10 antibodySCYA8
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, May play a role in neoplasia and inflammatory host responses, This protein can bind heparin, The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Cellular Localization Secreted
Tissue Specificity Highest expression found in the small intestine and peripheral blood cells, intermediate levels seen in the heart, placenta, lung, skeletal muscle, thymus, colon, ovary, spinal cord and pancreas, low levels seen in the brain, liver, spleen and prostate
Swiss-Prot Key

 

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