Anti-CCNA2 Antibody

Rs. 45,619.00
SKU stj29947

General Information

Product name Anti-CCNA2 Antibody
Short Description Rabbit polyclonal to CCNA2
Description The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-CCNA2 Antibody
Immunogen A synthetic peptide of human CCNA2
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 48.6 kDa
Database Links
Alternative Names CCNA2Cyclin-A2 antibodyCyclin-A antibodyCyclin ACCNA2 antibodyCCN1 antibodyCCNA
Function Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle, Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2, The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
Cellular Localization Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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