Anti-CCR2 Antibody

Rs. 45,619.00
SKU stj22962

General Information

Product name Anti-CCR2 Antibody
Short Description Rabbit polyclonal to CCR2
Description This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CCR2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 315-374 of human CCR2 (NP_001116513.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 41.9 kDa
Database Links
Alternative Names CCR2C-C chemokine receptor type 2 antibodyC-C CKR-2 antibodyCC-CKR-2 antibodyCCR-2 antibodyCCR2 antibodyMonocyte chemoattractant protein 1 receptor antibodyMCP-1-R antibodyCD antigen CD192CCR2 antibodyCMKBR2
Function Receptor for the CCL2, CCL7 and CCL13 chemokines Alternative coreceptor with CD4 for HIV-1 infection.
Cellular Localization Cell membrane
Tissue Specificity Expressed by monocytes and il2-activated nk cells.
Swiss-Prot Key

 

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