Anti-CD164 antibody

Rs. 50,211.00
SKU stj92095

General Information

Product name Anti-CD164 antibody
Short Description
Description Rabbit polyclonal to CD164.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:20000
Protein Name Anti-CD164 antibody
Immunogen Synthesized peptide derived from human CD164
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 20.011 kDa
Database Links
Alternative Names Sialomucin core protein 24 antibody
MUC-24 antibody
Endolyn antibody
Multi-glycosylated core protein 24 antibody
MGC-24 antibody
MGC-24v antibody
CD antigen CD164 antibody
Function Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34(+) cells to the stroma and by negatively regulating CD34(+)CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes .
Cellular Localization Lysosome membrane Endosome membrane Cell membrane Isoform 2: Secreted
Tissue Specificity Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells.
Swiss-Prot Key

 

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