Anti-CD247 Antibody

Rs. 68,577.00
SKU stj73100

General Information

Product name Anti-CD247 Antibody
Short Description Goat polyclonal to CD247
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-CD247 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 18.7 kDa
Database Links
Alternative Names CD247T-cell surface glycoprotein CD3 zeta chain antibodyT-cell receptor T3 zeta chain antibodyCD antigen CD247CD247 antibodyCD3Z antibodyT3Z antibodyTCRZ
Function Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response, When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z, All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain, Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways ,
Cellular Localization Membrane
Tissue Specificity Cd3z is expressed in normal lymphoid tissue and in peripheral blood mononuclear cells (pbmcs) ,
Swiss-Prot Key

 

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