Anti-Cd2ap Antibody

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Rs. 34,800.00
Rs. 32,800.00
SKU stj110098

General Information

Product name Anti-Cd2ap Antibody
Short Description Rabbit polyclonal to CD2AP
Description This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name CD2-associated proteinAdapter protein CMSCas ligand with multiple SH3 domains
Immunogen A synthetic peptide of human CD2AP
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 71.5 kDa
Database Links
Alternative Names CD2APCD2-associated protein antibodyAdapter protein CMS antibodyCas ligand with multiple SH3 domainsCD2AP
Function Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton.
Cellular Localization Cytoplasm, cytoskeleton.
Tissue Specificity Widely expressed in fetal and adult tissues
Swiss-Prot Key

 

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