Anti-CD36 Antibody

Rs. 45,619.00
SKU stj22993

General Information

Product name Anti-CD36 Antibody
Short Description Rabbit polyclonal to CD36
Description The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-CD36 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 301-400 of human CD36 (NP_001120916.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.1 kDa
Database Links
Alternative Names CD36Platelet glycoprotein 4 antibodyFatty acid translocase antibodyFAT antibodyGlycoprotein IIIb antibodyGPIIIB antibodyLeukocyte differentiation antigen CD36 antibodyPAS IV antibodyPAS-4 antibodyPlatelet collagen receptor antibodyPlatelet glycoprotein IV antibodyGPIV antibodyThrombospondin receptor antibodyCD antigen CD36CD36 antibodyGP3B antibodyGP4
Function Multifunctional glycoprotein that acts as receptor for a broad range of ligands, Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides, They are generally multivalent and can therefore engage multiple receptors simultaneously, the resulting formation of CD36 clusters initiates signal transduction and internalization of receptor-ligand complexes, The dependency on coreceptor signaling is strongly ligand specific, Cellular responses to these ligands are involved in angiogenesis, inflammatory response, fatty acid metabolism, taste and dietary fat processing in the intestine (Probable), Binds long-chain fatty acids and facilitates their transport into cells, thus participating in muscle lipid utilization, adipose energy storage, and gut fat absorption (By similarity) Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and the internalization of particles independently of TLR signaling.
Cellular Localization Cell membrane
Tissue Specificity
Swiss-Prot Key

 

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