Anti-CD79a antibody

Rs. 50,211.00
SKU stj92142

General Information

Product name Anti-CD79a antibody
Short Description
Description Rabbit polyclonal to CD79a.
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:20000
Protein Name Anti-CD79a antibody
Immunogen Synthesized peptide derived from human CD79a
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 25 kDa
Database Links
Alternative Names B-cell antigen receptor complex-associated protein alpha chain antibody
Ig-alpha antibody
MB-1 membrane glycoprotein antibody
Membrane-bound immunoglobulin-associated protein antibody
Surface IgM-associated protein antibody
CD antigen CD79A antibody
IGA antibody
MB1 antibody
Function Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Cellular Localization Cell membrane. Single-pass type I membrane protein. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Tissue Specificity B-cells.
Swiss-Prot Key

 

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