Anti-CD79B Antibody

Rs. 45,619.00
SKU stj23012

General Information

Product name Anti-CD79B Antibody
Short Description Rabbit polyclonal to CD79B
Description The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-CD79B Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 29-159 of human CD79B (NP_000617.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 26 kDa
Database Links
Alternative Names CD79BB-cell antigen receptor complex-associated protein beta chain antibodyB-cell-specific glycoprotein B29 antibodyIg-beta antibodyImmunoglobulin-associated B29 protein antibodyCD antigen CD79bCD79B antibodyB29 antibodyIGB
Function Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation, Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Cellular Localization Cell membrane
Tissue Specificity B-cells
Swiss-Prot Key

 

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