Anti-CDA Antibody

Rs. 45,619.00
SKU stj23020

General Information

Product name Anti-CDA Antibody
Short Description Rabbit polyclonal to CDA
Description This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-CDA Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human CDA (NP_001776.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 16.2 kDa
Database Links
Alternative Names CDACytidine deaminase CDA antibodyCDD
Function This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
Cellular Localization
Tissue Specificity Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and t- as well as b-cell lines
Swiss-Prot Key

 

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