Anti-CDC14A Antibody

Rs. 61,689.00
SKU stj23021

General Information

Product name Anti-CDC14A Antibody
Short Description Rabbit polyclonal to CDC14A
Description The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.
Applications WB,IHC,FC
Dilution range WB 1:500 - 1:1000
IHC 1:20 - 1:50
FC 1:20 - 1:50
Protein Name Anti-CDC14A Antibody
Immunogen A synthetic Peptide of human CDC14A
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 66.6 kDa
Database Links
Alternative Names CDC14ADual specificity protein phosphatase CDC14A CDC14A
Function Dual-specificity phosphatase, Required for centrosome separation and productive cytokinesis during cell division, Dephosphorylates SIRT2 around early anaphase, May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.
Cellular Localization Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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