Anti-CDC25A Antibody

Rs. 45,619.00
SKU stj23024

General Information

Product name Anti-CDC25A Antibody
Short Description Rabbit polyclonal to CDC25A
Description CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Applications IHC
Dilution range IHC 1:50 - 1:200
Protein Name Anti-CDC25A Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 235-484 of human CDC25A (NP_963861.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 59.1 kDa
Database Links
Alternative Names CDC25AM-phase inducer phosphatase 1 CDC25A
Function Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression, Directly dephosphorylates CDK1 and stimulates its kinase activity, Also dephosphorylates CDK2 in complex with cyclin E, in vitro
Cellular Localization
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed