Anti-CDC5L Antibody

Rs. 45,619.00
SKU stj27506

General Information

Product name Anti-CDC5L Antibody
Short Description Rabbit polyclonal to CDC5L
Description The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:10 - 1:100
Protein Name Anti-CDC5L Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 563-802 of human CDC5L (NP_001244.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 92.3 kDa
Database Links
Alternative Names CDC5LCell division cycle 5-like protein antibodyCdc5-like protein antibodyPombe cdc5-related proteinCDC5L antibodyKIAA0432 antibodyPCDC5RP
Function DNA-binding protein involved in cell cycle control, May act as a transcription activator, Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing, The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Cellular Localization Nucleus
Tissue Specificity Ubiquitously expressed in both fetal and adult tissues.
Swiss-Prot Key

 

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