Anti-CDH3 Antibody

Rs. 61,689.00
SKU stj23046

General Information

Product name Anti-CDH3 Antibody
Short Description Rabbit polyclonal to CDH3
Description This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS).
Applications WB,IHC,FC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
FC 1:20 - 1:50
Protein Name Anti-CDH3 Antibody
Immunogen A synthetic peptide of human CDH3
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 91.4 kDa
Database Links
Alternative Names CDH3Cadherin-3 antibodyPlacental cadherin antibodyP-cadherinCDH3 antibodyCDHP
Function Cadherins are calcium-dependent cell adhesion proteins, They preferentially interact with themselves in a homophilic manner in connecting cells
Cellular Localization Cell membrane
Tissue Specificity Expressed in some normal epithelial tissues and in some carcinoma cell lines.
Swiss-Prot Key

 

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