Anti-CDH8 Antibody

Rs. 45,619.00
SKU stj116449

General Information

Product name Anti-CDH8 Antibody
Short Description Rabbit polyclonal to CDH8
Description This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Cadherin-8
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 500-610 of human CDH8 (NP_001787.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 88.3 kDa
Database Links
Alternative Names CDH8Cadherin-8CDH8
Function Cadherins are calcium-dependent cell adhesion proteins, They preferentially interact with themselves in a homophilic manner in connecting cells
Cellular Localization Cell membrane
Tissue Specificity Mainly expressed in brain, found in certain nerve cell lines, such as retinoblasts, glioma cells and neuroblasts
Swiss-Prot Key

 

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