Anti-CDK1 Antibody

Rs. 45,619.00
SKU stj23049

General Information

Product name Anti-CDK1 Antibody
Short Description Rabbit polyclonal to CDK1
Description The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications WB,IHC,IF,IP
Dilution range WB 1:200 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100
IP 1:50 - 1:100
Protein Name Anti-CDK1 Antibody
Immunogen A synthetic peptide of human CDK1
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 34.1 kDa
Database Links
Alternative Names CDK1Cyclin-dependent kinase 1 antibodyCDK1CDK1 antibodyCDC2 antibodyCDC28A antibodyCDKN1 antibodyP34CDC2
Function Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset
Cellular Localization Nucleus, Cytoplasm, Mitochondrion, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Cytoplasm, cytoskeleton, spindle.
Tissue Specificity Isoform 2 is found in breast cancer tissues
Swiss-Prot Key

 

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