Anti-CDK14 Antibody

Rs. 57,098.00
SKU stj117185

General Information

Product name Anti-CDK14 Antibody
Short Description Rabbit polyclonal to CDK14
Description
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Cyclin-dependent kinase 14
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 312-451 of human CDK14 (NP_036527.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.1 kDa
Database Links
Alternative Names CDK14Cyclin-dependent kinase 14 CDK14 antibodyKIAA0834 antibodyPFTK1
Function Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin, Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway, Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3, Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo, May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
Cellular Localization Cell membrane
Tissue Specificity Highly expressed in brain, pancreas, kidney, heart, testis and ovary, also detected at lower levels in other tissues except in spleen and thymus where expression is barely detected.
Swiss-Prot Key

 

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