General Information
| Product name | Anti-CDK16 Antibody |
|---|---|
| Short Description | Rabbit polyclonal to CDK16 |
| Description | The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Applications | WB,IF |
| Dilution range | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| Protein Name | Cyclin-dependent kinase 16 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 277-496 of human CDK16 (NP_006192.1). |
| Storage Instruction | Store at -20℃. Avoid freeze / thaw cycles. |
| Type of Usage | For Research Use Only (RUO). |
Product Properties
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | Human,Mouse,Rat |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Isotype | IgG |
| Formulation | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Target
| Gene ID | |
|---|---|
| Gene Symbol | |
| Molecular Weight | 55.7 kDa |
| Database Links | |
| Alternative Names | CDK16Cyclin-dependent kinase 16 CDK16 antibodyPCTAIRE1 antibodyPCTK1 |
| Function | Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis, Regulates GH1 release by brain neurons, Phosphorylates NSF, and thereby regulates NSF oligomerization, Required for normal spermatogenesis, Regulates neuron differentiation and dendrite development (By similarity), Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels, Can phosphorylate CCNY at 'Ser-336' (in vitro). |
| Cellular Localization | Cytoplasm, Cytoplasmic vesicle, secretory vesicle, Cell membrane |
| Tissue Specificity | Detected in pancreas islets (at protein level), detected in brain and pancreas. |
| Swiss-Prot Key |