Anti-CDKN2D Antibody

Rs. 45,619.00
SKU stj28639

General Information

Product name Anti-CDKN2D Antibody
Short Description Rabbit polyclonal to CDKN2D
Description The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-CDKN2D Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-166 of human CDKN2D (NP_001791.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 17.7 kDa
Database Links
Alternative Names CDKN2DCyclin-dependent kinase 4 inhibitor D antibodyp19-INK4dCDKN2D
Function Interacts strongly with CDK4 and CDK6 and inhibits them.
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

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