Anti-CDS1 Antibody

Rs. 45,619.00
SKU stj115706

General Information

Product name Anti-CDS1 Antibody
Short Description Rabbit polyclonal to CDS1
Description Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Phosphatidate cytidylyltransferase 1
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human CDS1 (NP_001254.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.3 kDa
Database Links
Alternative Names CDS1Phosphatidate cytidylyltransferase 1 CDS1 antibodyCDS
Function Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin, Overexpression may amplify cellular signaling responses from cytokines, May also play an important role in the signal transduction mechanism of retina and neural cells
Cellular Localization Endoplasmic reticulum membrane
Tissue Specificity Expressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate, highly expressed in fetal kidney, lung and brain, lower level in fetal liver
Swiss-Prot Key

 

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