Anti-CDYL Antibody

Rs. 45,619.00
SKU stj28014

General Information

Product name Anti-CDYL Antibody
Short Description Rabbit polyclonal to CDYL
Description Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CDYL Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 245-544 of human CDYL (NP_004815.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 66.5 kDa
Database Links
Alternative Names CDYLChromodomain Y-like protein antibodyCDY-like antibodyCrotonyl-CoA hydrataseCDYL antibodyCDYL1
Function Chromatin reader protein that recognizes and binds histone H3 trimethylated at 'Lys-9', dimethylated at 'Lys-27' and trimethylated at 'Lys-27' (H3K9me3, H3K27me2 and H3K27me3, respectively) , Acts as a negative regulator of isoform 2 by displacing isoform 2 from chromatin.
Cellular Localization Nucleus.
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

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