Anti-CFP Antibody

Rs. 45,619.00
SKU stj27351

General Information

Product name Anti-CFP Antibody
Short Description Rabbit polyclonal to CFP
Description This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-CFP Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 190-469 of human CFP (NP_001138724.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 51.3 kDa
Database Links
Alternative Names CFPProperdin antibodyComplement factor PCFP antibodyPFC
Function A positive regulator of the alternate pathway of complement, It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
Cellular Localization Secreted
Tissue Specificity
Swiss-Prot Key

 

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