Anti-CHAF1B Antibody

Rs. 45,619.00
SKU stj28015

General Information

Product name Anti-CHAF1B Antibody
Short Description Rabbit polyclonal to CHAF1B
Description Chromatin assembly factor I (CAF-I) is required for the assembly of histone octamers onto newly-replicated DNA. CAF-I is composed of three protein subunits, p50, p60, and p150. The protein encoded by this gene corresponds to the p60 subunit and is required for chromatin assembly after replication. The encoded protein is differentially phosphorylated in a cell cycle-dependent manner. In addition, it is normally found in the nucleus except during mitosis, when it is released into the cytoplasm. This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100
Protein Name Anti-CHAF1B Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 270-559 of human CHAF1B (NP_005432.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 61.5 kDa
Database Links
Alternative Names CHAF1BChromatin assembly factor 1 subunit B antibodyCAF-1 subunit B antibodyChromatin assembly factor I p60 subunit antibodyCAF-I 60 kDa subunit antibodyCAF-I p60 antibodyM-phase phosphoprotein 7CHAF1B antibodyCAF1A antibodyCAF1P60 antibodyMPHOSPH7 antibodyMPP7
Function Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair, Assembles histone octamers onto replicating DNA in vitro, CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA
Cellular Localization Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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