Anti-CHD1L Antibody

Rs. 45,619.00
SKU stj116477

General Information

Product name Anti-CHD1L Antibody
Short Description Rabbit polyclonal to CHD1L
Description This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Chromodomain-helicase-DNA-binding protein 1-like
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 320-570 of human CHD1L (NP_001243267.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 101 kDa
Database Links
Alternative Names CHD1LChromodomain-helicase-DNA-binding protein 1-like CHD1L antibodyALC1
Function DNA helicase which plays a role in chromatin-remodeling following DNA damage, Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair, Able to catalyze nucleosome sliding in an ATP-dependent manner, Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.
Cellular Localization Nucleus.
Tissue Specificity Frequently overexpressed in hepatomacellular carcinomas.
Swiss-Prot Key

 

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