Anti-CHIA Antibody

Rs. 45,619.00
SKU stj116205

General Information

Product name Anti-CHIA Antibody
Short Description Rabbit polyclonal to CHIA
Description The protein encoded by this gene degrades chitin, which is found in the cell wall of most fungi as well as in arthropods and some nematodes. The encoded protein can also stimulate interleukin 13 expression, and variations in this gene can lead to asthma susceptibility. Several transcript variants encoding a few different isoforms have been found for this gene.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Acidic mammalian chitinaseAMCase
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human CHIA (NP_001244932.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 52.3 kDa
Database Links
Alternative Names CHIAAcidic mammalian chitinase antibodyAMCaseCHIA
Function Degrades chitin and chitotriose, May participate in the defense against nematodes, fungi and other pathogens, Plays a role in T-helper cell type 2 (Th2) immune response, Contributes to the response to IL-13 and inflammation in response to IL-13, Stimulates chemokine production by pulmonary epithelial cells, Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1, Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding.
Cellular Localization Secreted, Cytoplasm
Tissue Specificity Detected in lung epithelial cells from asthma patients (at protein level), highly expressed in stomach, detected at lower levels in lung.
Swiss-Prot Key

 

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