Anti-CHRFAM7A Antibody

Rs. 45,619.00
SKU stj114477

General Information

Product name Anti-CHRFAM7A Antibody
Short Description Rabbit polyclonal to CHRFAM7A
Description The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name CHRNA7-FAM7A fusion proteinCHRNA7-DR1D-10
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CHRFAM7A (NP_647536.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 46.2 kDa
Database Links
Alternative Names CHRFAM7ACHRNA7-FAM7A fusion protein antibodyCHRNA7-DR1 antibodyD-10CHRFAM7A
Function
Cellular Localization Membrane
Tissue Specificity Expressed in hippocampus.
Swiss-Prot Key

 

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