Anti-CHRNA1 Antibody

Rs. 45,619.00
SKU stj27259

General Information

Product name Anti-CHRNA1 Antibody
Short Description Rabbit polyclonal to CHRNA1
Description The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CHRNA1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 105-220 of human CHRNA1 (NP_000070.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 54.5 kDa
Database Links
Alternative Names CHRNA1Acetylcholine receptor subunit alphaCHRNA1 antibodyACHRA antibodyCHNRA
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Cellular Localization Cell junction, synapse, postsynaptic cell membrane
Tissue Specificity Isoform 1 is only expressed in skeletal muscle, isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus
Swiss-Prot Key

 

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