Anti-CHRNA6 Antibody

Rs. 45,619.00
SKU stj116016

General Information

Product name Anti-CHRNA6 Antibody
Short Description Rabbit polyclonal to CHRNA6
Description This gene encodes an alpha subunit of neuronal nicotinic acetylcholine receptors. These receptors consist of five subunits and function as ion channels involved in neurotransmission. The encoded protein is a subunit of neuronal nicotinic acetylcholine receptors that mediate dopaminergic neurotransmission and are activated by acetylcholine and exogenous nicotine. Alternatively spliced transcript variants have been observed for this gene. Single nucleotide polymorphisms in this gene have been associated with both nicotine and alcohol dependence.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Neuronal acetylcholine receptor subunit alpha-6
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 350-440 of human CHRNA6 (NP_004189.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 56.9 kDa
Database Links
Alternative Names CHRNA6Neuronal acetylcholine receptor subunit alpha-6CHRNA6
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane
Cellular Localization Cell junction, synapse, postsynaptic cell membrane
Tissue Specificity
Swiss-Prot Key

 

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