Anti-CHST1 Antibody

Rs. 45,619.00
SKU stj115024

General Information

Product name Anti-CHST1 Antibody
Short Description Rabbit polyclonal to CHST1
Description This locus encodes a member of the keratin sulfotransferase family of proteins. The encoded enzyme catalyzes the sulfation of the proteoglycan keratin.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Carbohydrate sulfotransferase 1
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 62-411 of human CHST1 (NP_003645.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 46.7 kDa
Database Links
Alternative Names CHST1Carbohydrate sulfotransferase 1 CHST1
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) residues of keratan, Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer, The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated, May function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins, Participates in biosynthesis of selectin ligands, Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation.
Cellular Localization Golgi apparatus membrane
Tissue Specificity Widely expressed at low level, expressed in brain and skeletal muscle, expressed by high endothelial cells (hevs) and leukocytes.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed
Print Friendly and PDF