Anti-CHST10 Antibody

Rs. 45,619.00
SKU stj26611

General Information

Product name Anti-CHST10 Antibody
Short Description Rabbit polyclonal to CHST10
Description This protein encoded by this gene transfers sulfate to the C-3 hydroxyl of terminal glucuronic acid of protein- and lipid-linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan; HNK-1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.
Applications WB
Dilution range WB 1:200 - 1:500
Protein Name Anti-CHST10 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 30-250 of human CHST10 (NP_004845.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 42.2 kDa
Database Links
Alternative Names CHST10Carbohydrate sulfotransferase 10 CHST10
Function Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides, Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult, May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis.
Cellular Localization Golgi apparatus membrane
Tissue Specificity In fetal tissues, it is predominantly expressed in brain, and weakly expressed in lung, kidney and liver, in adult, it is highly expressed in brain, testis, ovary, expressed at intermediate level in heart, pancreas, skeletal muscle, spleen and thymus, and weakly expressed in other tissues, in brain, it is expressed at higher level in the frontal lobe.
Swiss-Prot Key

 

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