Anti-CITED2 Antibody

Rs. 45,619.00
SKU stj114697

General Information

Product name Anti-CITED2 Antibody
Short Description Rabbit polyclonal to CITED2
Description The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Cbp/p300-interacting transactivator 2MSG-related protein 1MRG-1P35srj
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-275 of human CITED2 (NP_001161861.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 28.5 kDa
Database Links
Alternative Names CITED2Cbp/p300-interacting transactivator 2 antibodyMSG-related protein 1 antibodyMRG-1 antibodyP35srjCITED2 antibodyMRG1
Function Transcriptional coactivator of the p300/CBP-mediated transcription complex, Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimulate TFAP2-mediated transcriptional activation, Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex, Stimulates the peroxisome proliferator-activated receptors PPARA transcriptional activity, Enhances estrogen-dependent transactivation mediated by estrogen receptors, Acts also as a transcriptional corepressor
Cellular Localization Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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