Anti-CKMT1A Antibody

Rs. 45,619.00
SKU stj23147

General Information

Product name Anti-CKMT1A Antibody
Short Description Rabbit polyclonal to CKMT1A
Description Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CKMT1A Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 258-417 of human CKMT1A (NP_001015001.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 47 kDa
Database Links
Alternative Names CKMT1ACreatine kinase U-type antibodymitochondrial CKMT1A antibodyCKMT; antibodyCKMT1B antibodyCKMT
Function Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e,g, creatine phosphate), Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa
Cellular Localization Mitochondrion inner membrane
Tissue Specificity
Swiss-Prot Key

 

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