Anti-CLCN4 Antibody

Rs. 45,619.00
SKU stj115735

General Information

Product name Anti-CLCN4 Antibody
Short Description Rabbit polyclonal to CLCN4
Description The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name H(+/Cl(-exchange transporter 4Chloride channel protein 4ClC-4Chloride transporter ClC-4
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 600-700 of human CLCN4 (NP_001821.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 84.9 kDa
Database Links
Alternative Names CLCN4H(+ antibody/Cl(- antibodyexchange transporter 4 antibodyChloride channel protein 4 antibodyClC-4 antibodyChloride transporter ClC-4CLCN4
Function Proton-coupled chloride transporter, Functions as antiport system and exchanges chloride ions against protons.
Cellular Localization Early endosome membrane
Tissue Specificity Abundant in skeletal muscle and also detectable in brain and heart
Swiss-Prot Key

 

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