Anti-CLCN5 Antibody

Rs. 45,619.00
SKU stj27674

General Information

Product name Anti-CLCN5 Antibody
Short Description Rabbit polyclonal to CLCN5
Description This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-CLCN5 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 637-816 of human CLCN5 (NP_001121370.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 83.1 kDa
Database Links
Alternative Names CLCN5H(+ antibody/Cl(- antibodyexchange transporter 5 antibodyChloride channel protein 5 antibodyClC-5 antibodyChloride transporter ClC-5CLCN5 antibodyCLCK2
Function Proton-coupled chloride transporter, Functions as antiport system and exchanges chloride ions against protons, Important for normal acidification of the endosome lumen, May play an important role in renal tubular function
Cellular Localization Golgi apparatus membrane
Tissue Specificity Kidney, moderately expressed in aortic vascular smooth muscle and endothelial cells, and at a slightly higher level in the coronary vascular smooth muscle.
Swiss-Prot Key

 

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