Anti-CLCN7 Antibody

Rs. 45,619.00
SKU stj28966

General Information

Product name Anti-CLCN7 Antibody
Short Description Rabbit polyclonal to CLCN7
Description The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-CLCN7 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 626-805 of human CLCN7 (NP_001278.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


Gene ID
Gene Symbol
Molecular Weight 88.7 kDa
Database Links
Alternative Names CLCN7H(+ antibody/Cl(- antibodyexchange transporter 7 antibodyChloride channel 7 alpha subunit antibodyChloride channel protein 7 antibodyClC-7CLCN7
Function Slowly voltage-gated channel mediating the exchange of chloride ions against protons, Functions as antiporter and contributes to the acidification of the lysosome lumen.
Cellular Localization Lysosome membrane
Tissue Specificity Brain, testis, muscle and kidney
Swiss-Prot Key


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