Anti-CLDN4 Antibody

Rs. 45,619.00
SKU stj114778

General Information

Product name Anti-CLDN4 Antibody
Short Description Rabbit polyclonal to CLDN4
Description The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Claudin-4Clostridium perfringens enterotoxin receptorCPE-RCPE-receptorWilliams-Beuren syndrome chromosomal region 8 protein
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human CLDN4 (NP_001296.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 22.1 kDa
Database Links
Alternative Names CLDN4Claudin-4 antibodyClostridium perfringens enterotoxin receptor antibodyCPE-R antibodyCPE-receptor antibodyWilliams-Beuren syndrome chromosomal region 8 proteinCLDN4 antibodyCPER antibodyCPETR1 antibodyWBSCR8
Function Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney, Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts, Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Cellular Localization Cell junction, tight junction
Tissue Specificity
Swiss-Prot Key

 

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