Anti-Cleaved-Factor B Bb (K260) antibody

Rs. 50,211.00
SKU stj90079

General Information

Product name Anti-Cleaved-Factor B Bb (K260) antibody
Short Description
Description Rabbit polyclonal to Cleaved-Factor B Bb (K260).
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:20000
Protein Name Anti-Cleaved-Factor B Bb (K260) antibody
Immunogen Synthesized peptide derived from human Factor B Bb
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 57/85 kDa
Database Links
Alternative Names Cleaved-Factor B Bb (K260)
Complement factor B antibody
C3/C5 convertase antibody
Glycine-rich beta glycoprotein antibody
GBG antibody
PBF2 antibody
Properdin factor B antibody
Complement factor B Ba fragment antibody
Complement factor B Bb fragment antibody
BF antibody
BFD antibody
Function Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Cellular Localization Secreted.
Tissue Specificity
Swiss-Prot Key

 

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