Anti-CLEC12A Antibody

Rs. 45,619.00
SKU stj28006

General Information

Product name Anti-CLEC12A Antibody
Short Description Rabbit polyclonal to CLEC12A
Description This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-CLEC12A Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 66-265 of human CLEC12A (NP_612210.4).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 30.8 kDa
Database Links
Alternative Names CLEC12AC-type lectin domain family 12 member A antibodyC-type lectin-like molecule 1 antibodyCLL-1 antibodyDendritic cell-associated lectin 2 antibodyDCAL-2 antibodyMyeloid inhibitory C-type lectin-like receptor antibodyMICLCLEC12A antibodyCLL1 antibodyDCAL2 antibodyMICL
Function Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Cellular Localization Cell membrane.
Tissue Specificity Detected in normal myeloid cells and in acute myeloid leukemia cells, detected in neutrophils, eosinophils, monocytes and dendritic cells, detected in spleen macrophage-rich red pulp and in lymph node (at protein level), detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages.
Swiss-Prot Key

 

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