Anti-CLN5 antibody

Rs. 50,211.00
SKU stj92341

General Information

Product name Anti-CLN5 antibody
Short Description
Description Rabbit polyclonal to CLN5.
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:10000
Protein Name Anti-CLN5 antibody
Immunogen Synthesized peptide derived from human CLN5
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 48 kDa
Database Links
Alternative Names Ceroid-lipofuscinosis neuronal protein 5 antibody
Protein CLN5 antibody
Ceroid-lipofuscinosis neuronal protein 5, secreted form antibody
Function Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane .
Cellular Localization Ceroid-lipofuscinosis neuronal protein 5, secreted form: Lysosome Ceroid-lipofuscinosis neuronal protein 5: Membrane. An amphipathic anchor region facilitates its association with the membrane.
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

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