Anti-CLPS Antibody

Rs. 45,619.00
SKU stj28447

General Information

Product name Anti-CLPS Antibody
Short Description Rabbit polyclonal to CLPS
Description The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Three transcript variants encoding different isoforms have been found for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:10 - 1:100
Protein Name Anti-CLPS Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 18-112 of human CLPS (NP_001823.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 12 kDa
Database Links
Alternative Names CLPSColipaseCLPS
Function Colipase is a cofactor of pancreatic lipase, It allows the lipase to anchor itself to the lipid-water interface, Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase
Cellular Localization Secreted
Tissue Specificity Expressed by the pancreas
Swiss-Prot Key

 

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