Anti-CNR1 Antibody

Rs. 61,689.00
SKU stj113402

General Information

Product name Anti-CNR1 Antibody
Short Description Rabbit polyclonal to CNR1
Description This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
Applications WB
Dilution range WB 1:200 - 1:1000
Protein Name Cannabinoid receptor 1CB-RCB1CANN6
Immunogen A synthetic peptide of human CNR1
Storage Instruction Store at 4℃ (regular) or -20℃ (long term). Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 52.9 kDa
Database Links
Alternative Names CNR1Cannabinoid receptor 1 antibodyCB-R antibodyCB1 antibodyCANN6CNR1 antibodyCNR
Function G-protein coupled receptor for endogenous cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG), as well as phytocannabinoids, such as delta(9)-tetrahydrocannabinol (THC).
Cellular Localization Cell membrane.
Tissue Specificity Widely expressed, with highest levels in fetal and adult brain, expression levels of isoform 2 and isoform 3 are much lower than those of isoform 1.
Swiss-Prot Key

 

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