Anti-CNTFR Antibody

Rs. 45,619.00
SKU stj23187

General Information

Product name Anti-CNTFR Antibody
Short Description Rabbit polyclonal to CNTFR
Description This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.
Applications WB
Dilution range WB 1:400 - 1:2000
Protein Name Anti-CNTFR Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 190-340 of human CNTFR (NP_001833.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 40.6 kDa
Database Links
Alternative Names CNTFRCiliary neurotrophic factor receptor subunit alpha antibodyCNTF receptor subunit alpha antibodyCNTFR-alphaCNTFR
Function Binds to CNTF, The alpha subunit provides the receptor specificity
Cellular Localization Cell membrane
Tissue Specificity Nervous system and skeletal muscle
Swiss-Prot Key

 

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