Anti-COIL Antibody

Rs. 45,619.00
SKU stj28511

General Information

Product name Anti-COIL Antibody
Short Description Rabbit polyclonal to COIL
Description The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-COIL Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human COIL (NP_004636.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 62.6 kDa
Database Links
Alternative Names COILCoilin antibodyp80-coilinCOIL antibodyCLN80
Function Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
Cellular Localization Nucleus
Tissue Specificity Found in all the cell types examined
Swiss-Prot Key

 

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