Anti-COL17A1 antibody

Rs. 50,211.00
SKU stj92379

General Information

Product name Anti-COL17A1 antibody
Short Description
Description Rabbit polyclonal to COL17A1.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-COL17A1 antibody
Immunogen Synthesized peptide derived from human COL17A1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 150.419 kDa
Database Links
Alternative Names Collagen alpha-1 antibody
XVII chain antibody
180 kDa bullous pemphigoid antigen 2 antibody
Bullous pemphigoid antigen 2 antibody
120 kDa linear IgA disease antigen antibody
120 kDa linear IgA dermatosis antigen antibody
Linear IgA disease antigen 1 antibody
LAD-1 antibody
97 kDa linear IgA disease antigen antibody
97 kDa linear IgA bullous dermatosis antigen antibody
97 kDa LAD antigen antibody
97-LAD antibody
Linear IgA bullous disease antigen of 97 kDa antibody
LABD97 antibody
BP180 antibody
BPAG2 antibody
Function May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.; The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies.
Cellular Localization Cell junction, hemidesmosome. Membrane. Single-pass type II membrane protein. Localized along the plasma membrane of the hemidesmosome.. 120 kDa linear IgA disease antigen: Secreted, extracellular space, extracellular matrix, basement membrane. Exclusively localized to anchoring filaments. Localized to the epidermal side of split skin.. 97 kDa linear IgA disease antigen: Secreted, extracellular space, extracellular matrix, basement membrane. Localized in the lamina lucida beneath the hemidesmosomes.
Tissue Specificity Detected in skin . In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells (at protein level) . Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves.
Swiss-Prot Key

 

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