Anti-COL2A1 Antibody

Rs. 45,619.00
SKU stj23191

General Information

Product name Anti-COL2A1 Antibody
Short Description Rabbit polyclonal to COL2A1
Description This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-COL2A1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1159-1418 of human COL2A1 (NP_149162.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 141.8 kDa
Database Links
Alternative Names COL2A1Collagen alpha-1(II antibodychain antibodyAlpha-1 type II collagenCOL2A1
Function Type II collagen is specific for cartilaginous tissues, It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces
Cellular Localization Secreted, extracellular space, extracellular matrix
Tissue Specificity Isoform 2 is highly expressed in juvenile chondrocyte and low in fetal chondrocyte.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed
Print Friendly and PDF